What is niclosamide most effective against?

[Davidbrownm05]

1. Broad-Spectrum Use: It demonstrates efficacy against a range of tapeworm species, making it a broad-spectrum anthelmintic.
2. Oral Administration: Typically administered orally, niclosamide is available in tablet or chewable form for convenient use.
3. Low Absorption: Niclosamide is minimally absorbed by the body, acting primarily within the gastrointestinal tract, which contributes to its targeted action against intestinal parasites.
4. Safety Profile: Generally considered safe when used as directed, niclosamide has a favorable safety profile with limited systemic absorption.
5. Synergy with Praziquantel: In some cases, niclosamide may be used in combination with praziquantel, another anthelmintic, to enhance efficacy, particularly in treating certain tapeworm infections.
6. Public Health Programs: Niclosamide is included in public health programs targeting parasitic infections, especially in regions where sanitation and hygiene play crucial roles in disease prevention.
7. Prescription Medication: It is available only with a prescription, and proper medical guidance is essential to determine the appropriate dosage and duration of treatment.
8. Resistance Concerns: While resistance to niclosamide is not as prevalent as with some other anthelmintics, monitoring and addressing resistance remain important considerations in public health strategies.
9. Prevalent in Veterinary Medicine: Niclosamide is also used in veterinary medicine to treat parasitic infections in animals, contributing to overall disease control efforts.
10. Research for Anticancer Properties: Beyond its use as an anthelmintic, ongoing research explores niclosamide's potential anticancer properties, showing promise in laboratory studies for certain cancer types.